Correlation with thermal behaviour.

CLAIRITY™ THERMAL is a high-precision microscope image analysis software that merges hot stage microscopy with AI-driven imaging to quantify thermal transitions and microstructural changes in real time. The platform converts thermal imaging into actionable data, capturing material behavior such as melting, crystallization, and degradation, while enabling morphological classification across heating and cooling cycles.

Designed for research and regulated labs, the system supports particle size and size distribution analysis during thermal stress, providing real-time D10, D50, and D90 values using advanced image segmentation. Whether in deformulation analysis, stability testing, or formulation development, CLAIRITY THERMAL combines optical imaging and programmable temperature profiling for traceable, in-situ observations.

Gallery Image
Gallery Image
Gallery Image
Gallery Image
Gallery Image
Gallery Image

Its compatibility with various imaging systems and adherence to 21 CFR Part 11 make it a scalable, compliant solution for particle size analysis in the pharmaceutical and food industries.

Download Brochure
×

Challenges We Address

Manual interpretation of thermal transitions

Manual interpretation of thermal transitions

Detecting melting, crystallization, or glass transitions often depends on operator observation. CLAIRITY™ THERMAL applies automated detection techniques using temperature-synchronized analysis, improving objectivity across thermal scans.

Lack of morphology-linked thermal data

Lack of morphology-linked thermal data

DSC and TGA quantify heat flow but overlook shape changes. This thermal image analysis software connects particle size distributions with thermal shifts by capturing visual transitions through hot stage optical microscopy.

Inability to track changes over time

Inability to track changes over time

Static thermal outputs limit understanding of polymorphic shifts or particle coalescence. Time-lapse functionality in CLAIRITY THERMAL enables frame-by-frame thermal event review, reinforcing kinetic analysis.

 Generic heating protocols

Generic heating protocols

Non-specific ramping conditions fail to simulate real-world formulations. Users can create custom thermal profiles with programmable ramp rates and hold times, enhancing material-specific evaluation.

Non-compliant documentation

Non-compliant documentation

Manual workflows do not align with GxP and audit requirements. This thermal analysis software supports secure, audit-ready reporting with e-signatures, user controls, and traceable logs.

 Limited platform integration

Limited platform integration

Many systems restrict microscope options. CLAIRITY™ THERMAL integrates with most optical and polarized microscopes, ensuring flexibility in lab environments.

Benefits

  • Visual and Quantitative Thermal Event Detection
  • Morphology-Linked Classification
  • Automated, Traceable Reporting
  • Cross-Compatible Microscopy Setup
  • Custom Thermal Profiling

Visual and Quantitative Thermal Event Detection

  • Captures transitions like melting, glass transition, and crystallization in real time
  • Offers kinetic analysis using temperature-tagged imaging sequences

Morphology-Linked Classification

  • Computes distribution particle size metrics including D10, D50, D90 during thermal cycling
  • Supports particle size distribution analysis with statistical accuracy

Automated, Traceable Reporting

  • Compliant with 21 CFR Part 11 with audit trails and e-signature support
  • Delivers structured, tamper-proof reports for QA and regulatory filing

Cross-Compatible Microscopy Setup

  • Works with optical, digital, and polarized microscope systems
  • Enhances existing setups with thermal intelligence and hot stage microscopy principle

Custom Thermal Profiling

  • Tailors temperature conditions to material-specific requirements
  • Enables simulation of real-world conditions for particle size distribution analyzer workflows

Related Applications

Precision imaging across critical applications

API Particle Characterisation

API Particle Characterisation

Deformulation Analysis

Deformulation Analysis

Excipient Particle Characterization

Excipient Particle Characterization

Globule Size Determination in semi-solid dosage forms

Globule Size Determination in semi-solid dosage forms

Hot Stage Microscopy

Hot Stage Microscopy

Industries

Serving domains that depend on clarity

Academia
Academia
Additive Manufacturing
Additive Manufacturing
Biologics
Biologics
Cannabis
Cannabis
Chemicals and Materials science
Chemicals and Materials science
Cosmetics
Cosmetics
Dairy
Dairy
Food & Beverages
Food & Beverages
Forensic science
Forensic science
Mining and Minerals
Mining and Minerals
Pharmaceutical
Pharmaceutical

Enquire Now

Start the exchange that brings precision to your workflow

    Related Products