Are you facing problems in the analysis of the cream & gel samples?

Observing the Cream sample and globule sample is difficult sometimes to analyse particle size with the help of laser diffraction because in laser diffraction the sample should be diluted form (i.e. not good for sensitive APIs which might get diluted while dissolving). Laser diffraction method the rays pass through the diluted solution and pick up the particles present in the solution but due to the ray falling on particles, it creates a certain angle of deviation by which the laser diffraction considers the particles as round shape or cylindrical shape (no other shape of particles was shown). While observing the cream samples under a microscope, first less amount of sample requirement, and no need to dilute the cream with dilution solvent, the observation of globules with IPV-developed software it becomes easy to analyse globules samples. The cream is in the semi-solid form it is difficult or not easy to flow in laser diffraction, and sometimes it may get problems. For any semi-solid material or topical material (cream, gel, aerosol, ointment etc.) for this microscopy analysis is very easy and accurate.